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Index > Protein center > DEFB103A(Gene name) > Human
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  • DEFB103A (Gene name),
  • Beta-defensin 103 (Protein name ),  D103A_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Related Databases
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  • Citations  (3)
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  • Gene name:
    DEFB103A(BD3;DEFB103;DEFB3);
    Protein name:
    Beta-defensin 103;
    Alternative:
    Defensin, beta 103;Beta-defensin 3(BD-3;DEFB-3;HBD3;hBD-3);Defensin-like protein;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Exhibits antimicrobial activity against Gram-positive bacteria S.aureus and S.pyogenes, Gram-negative bacteria P.aeruginosa and E.coli and the yeast C.albicans. Kills multiresistant S.aureus and vancomycin-resistent E.faecium. No significant hemolytic activity was observed.
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    67
    Sequence:
    50:
    MRIHYLLFAL | LFLFLVPVPG | HGGIINTLQK | YYCRVRGGRC | AVLSCLPKEE | 
    67:
    QIGKCSTRGR | KCCRRKK
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    UniGene:
    Pfam:
    String:
    MIM:
    Uniprot:
     
    FOR
    ELISA Kit for Human Beta-defensin 103
    Cat.:
    E0276h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Beta-defensin 103
    Cat.:
    U0276h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    Polyclonal Antibody for Human Beta-defensin 103
    Cat.:
    P0276Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Beta-defensin 103
    Protein for Human Beta-defensin 103

    R&D Technical Data
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Isolation and characterization of human beta-defensin-3, a novel human inducible peptide antibiotic."
      Harder J. , Bartels J. , Christophers E. , Schroeder J.-M.
      J. Biol. Chem.276:5707-5713(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];PROTEIN SEQUENCE OF 23-67;FUNCTION;TISSUE SPECIFICITY;INDUCTION;MASS SPECTROMETRY
      tissue: Keratinocyte.
      tissue: Lung epithelium.
      tissue: Tracheal epithelium.
    2. 2.
      "Identification of a novel, multifunctional beta-defensin (human beta-defensin 3) with specific antimicrobial activity. Its interaction with plasma membranes of Xenopus oocytes and the induction of macrophage chemoattraction."
      Conejo-Garcia J.-R. , Jaumann F. , Schulz S. , Krause A. , Rodriguez-Jimenez F.-J. , Forssmann U. , Adermann K. , Kluever E. , Vogelmeier C. , Becker D. , Hedrich R. , Forssmann W.-G. , Bals R.
      Cell Tissue Res.306:257-264(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];CHARACTERIZATION
    3. 3.
      "Discovery of new human beta-defensins using a genomics-based approach."
      Jia H.P. , Schutte B.C. , Schudy A. , Linzmeier R. , Guthmiller J.M. , Johnson G.K. , Tack B.F. , Mitros J.P. , Rosenthal A. , Ganz T. , McCray P.B. Jr.
      Gene263:211-218(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    4. 4.
      Imai Y.
      Submitted (2000-02) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    5. 5.
      "EST and genomic database mining yield novel human and mouse beta-defensins."
      Adler D.A. , Diamond G. , Sheppard P. , Holloway J. , Presnell S. , Jaspers S. , Whitmore T. , Fox B. , Gosink J. , Rixon M. , Gao Z. , Haldeman B. , O'Hara P.
      Submitted (2000-08) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    6. 6.
      "Cloning and expression of Chinese human beta defensin-3."
      Chen S. , He F. , Li R.
      Submitted (2002-05) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Tonsil.
    7. 7.
      "The solution structures of the human beta-defensins lead to a better understanding of the potent bactericidal activity of HBD3 against Staphylococcus aureus."
      Schibli D.J. , Hunter H.N. , Aseyev V. , Starner T.D. , Wiencek J.M. , McCray P.B. Jr. , Tack B.F. , Vogel H.J.
      J. Biol. Chem.277:8279-8289(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 23-67
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